The DNA: The new Ca’ di Dio hotel is set in a14th-century building, once home to variously; pilgrims, ‘fallen’ women and the elderly. There’s interiors by Patricia Urquiola and a warm and relaxed approach to five-star hospitality. The lagoon-facing site in Castello, on the edge of Arsenale, is hard to beat.

Seen: Wallpaper*

✅ free Wi-Fi • size matters: 66 rooms, including 57 suites (22-41m2) (237-441 sq ft) • hotel opened: 2021 • interior design: Patricia Urquiola ❌ no parking available • pets allowed • 24-hour front desk • wheelchair accessible