ABOUT YOU
Tired of endless surfing, scrolling and filtering finding the right place to stay? Here at DNA Hotels find our curated collection of the authentic and inspirational, our own finds plus your favourite bookmarked selection from travel and design publications. Search for experiences rather than just location, price and a place to lay your head. A hotel as a home away from home? We don't think so.
Newsletter Join The List, sign up to receive exclusive discounts and special offers Sign up

design-led hotel

Where Design Defines the Experience

This is the heart of DNA Hotels. A design-led hotel doesn’t have to be created by a famous architect or interior designer—it can be carefully designed from the ground up or have evolved organically over decades. What matters is that everything feels connected: architecture, interiors, furniture, materials, light and atmosphere. These are hotels with a clear point of view, where design isn’t decoration or a marketing label, but part of the character of the place and the way you experience it.

Canal House
Canal House | Amsterdam

Canal House

Canal House | Amsterdam, The Netherlands Historic Canal Elegance with a Dramatic Contemporary Twist Why DNA Hotels Loves It ● Three beautifully restored 17th-century canal houses transformed into one of Amsterdam's most atmospheric boutique hotels. ● Rich, theatrical interiors that combine historic architecture with bold contemporary design. ● A surprisingly large private garden oasis hidden…

read more
1024 681 Chiel
XVA Art Hotel
XVA Art Hotel | Dubai

XVA Art Hotel

XVA Art Hotel | Dubai Old Dubai's Creative Hideaway Why DNA Hotels Loves It ● One of Dubai's most authentic boutique stays, hidden within the winding lanes of the historic Al Fahidi district, where traditional architecture replaces glittering skyscrapers. ● A unique blend of heritage, contemporary Middle Eastern art, and intimate hospitality that feels more…

read more
512 768 Chiel
La Fiermontina
La Fiermontina | Lecce, Italy

La Fiermontina

La Fiermontina – Lecce, Italy An art-filled urban retreat where Puglian stone, family history and contemporary design meet behind Lecce’s ancient walls. Why DNA Hotels Loves It ● A deeply personal hotel inspired by Antonia Fiermonte, artist, model and muse, whose extraordinary life and relationships with sculptors René Letourneur and Jacques Zwobada shape the collection…

read more
512 768 Chiel
The Paramour Estate
The Paramour Estate | Los Angeles

The Paramour Estate

The Paramour Estate, Los Angeles Where Hollywood's Golden Age Meets Silver Lake's Creative Spirit Why DNA Hotels Loves It ● A legendary 1923 Mediterranean Revival estate whose remarkable history spans silent-film royalty, a convent, an artists' refuge, and one of Los Angeles' most extraordinary boutique stays. ● Original architecture, lavish gardens, frescoed interiors, and atmospheric…

read more
1920 1319 Chiel
UNAHOTELS Vittoria Firenze
UNAHOTELS Vittoria Firenze

UNAHOTELS Vittoria Firenze

UNAHOTELS Vittoria Firenze | Florence, Italy A Bold Design Hotel Where Fabio Novembre Reimagines Contemporary Florence Why DNA Hotels Loves It ● A fearless interior concept by renowned Italian architect and designer Fabio Novembre, where hospitality becomes immersive design. ● Striking public spaces filled with sculptural furniture, bold colour palettes, and artistic references to Florence's…

read more
1024 683 Chiel
21c Museum Hotel St. Louis
21c Museum Hotel St. Louis

21c Museum Hotel St. Louis

21c Museum Hotel St. Louis - Missouri, USA A former YMCA where contemporary art, historic architecture and a swimming pool share the same stage. Why DNA Hotels Loves It ● A 1920s Renaissance Revival YMCA has been brilliantly repurposed without erasing its sporting past — even the former basketball court is now a gallery. ●…

read more
1024 576 Chiel
The Jay
The Jay, Autograph Collection

The Jay

The Jay | San Francisco, California | USA Brutalist Architecture, Californian Warmth Why DNA Hotels Loves It ● A thoughtful transformation of John Portman's striking Brutalist landmark into one of San Francisco's most design-forward hotels. ● AvroKO masterfully balances sculptural architecture with warm, contemporary interiors inspired by the city's creative pioneers. ● A hotel that…

read more
980 596 Chiel
The Modernist Athens
The Modernist | Athens

The Modernist Athens

The Modernist Athens | Greece Design Precision with a Local Pulse Why DNA Hotels Loves It ● A beautifully transformed former embassy that brings mid-century modernism into contemporary Athens. ● Thoughtfully curated interiors filled with local art, design, craftsmanship, and cultural references. ● A rooftop terrace with Acropolis views that feels more like a stylish…

read more
950 1424 Chiel
The Fifth Avenue Hotel
The Fifth Avenue Hotel | New York

The Fifth Avenue Hotel

The Fifth Avenue Hotel | New York City, USA Gilded Age Grandeur Meets Fearless Contemporary Maximalism Why DNA Hotels Loves It ● A remarkable fusion of a restored 1907 Renaissance-style mansion and a striking contemporary glass tower in the heart of NoMad. ● Martin Brudnizki's exuberant interiors transform every room into a richly layered work…

read more
1024 683 Chiel
me and all hotel Flims
me and all hotel Flims

me and all hotel Flims

me and all hotel Flims, by Hyatt | SwitzerlandA colorful alpine escape where contemporary design, velvet textures, and mountain adventures come together at the foot of the Swiss Alps. Why DNA Hotels Loves It ● A refreshing alternative to traditional Swiss chalet hotels, replacing rustic clichés with bold contemporary design.● Rich jewel-toned interiors that bring…

read more
512 768 Chiel
Clarion Hotel Draken
Clarion Hotel Draken | Gothenburg

Clarion Hotel Draken

Clarion Hotel Draken, Gothenburg, Sweden Where Film, Design, and Culture Meet Above the City Skyline Why DNA Hotels Loves It ● A bold cultural landmark that seamlessly integrates Gothenburg’s historic Draken cinema into a contemporary design hotel. ● Interiors by acclaimed local studio Stylt that celebrate film, theatre, music, art, and design through immersive storytelling.…

read more
512 768 Chiel
Casa Hormiga
Casa Hormiga | Bacalar, Mexico

Casa Hormiga

Casa Hormiga | Bacalar, Mexico An intimate jungle retreat where wabi-sabi simplicity, handcrafted design, and slow living come together beside Mexico's Lagoon of Seven Colours. Why DNA Hotels Loves It ● A beautifully crafted boutique hotel that combines Mexican craftsmanship with understated contemporary design. ● Wellness is woven naturally into the experience through silence, rituals,…

read more
1024 683 Chiel