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Tired of endless surfing, scrolling and filtering finding the right place to stay? Here at DNA Hotels find our curated collection of the authentic and inspirational, our own finds plus your favourite bookmarked selection from travel and design publications. Search for experiences rather than just location, price and a place to lay your head. A hotel as a home away from home? We don't think so.
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wheelchair accessible

Where Good Hospitality Includes Everyone

Great hotels should be welcoming to as many people as possible. Wheelchair Accessible highlights hotels offering accessible rooms, step-free access or other facilities designed to make a stay easier for guests with reduced mobility. Accessibility needs are personal, however, and facilities can differ considerably between hotels. If you have specific requirements, always check the details directly with the hotel before booking.

25hours Hotel Langstrasse
25hours Hotel Langstrasse | Zürich

25hours Hotel Langstrasse

25hours Hotel Zürich Langstrasse, Switzerland An Eclectic Design Hotel Inspired by Zürich's Most Colourful Neighbourhood Why DNA Hotels Loves It ● Werner Aisslinger's bold interiors capture the creative energy and multicultural character of Langstrasse with colour, art, and playful design. ● A lively mix of local culture, contemporary art, music, and social spaces makes the…

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25hours Hotel Zürich West
25hours Hotel Zürich West

25hours Hotel Zürich West

25hours Hotel Zürich West, Switzerland A Playful Design Hotel at the Heart of Zürich's Creative Revival Why DNA Hotels Loves It ● Designed by Alfredo Häberli, the hotel transforms Zürich's industrial heritage into a colourful and highly personal design experience. ● Bold interiors, playful details, and lively social spaces perfectly reflect the creative energy of…

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25hours Hotel Altes Hafenamt
25hours Hotel Altes Hafenamt | Hamburg

25hours Hotel Altes Hafenamt

25hours Hotel Altes Hafenamt – Hamburg, Germany Hamburg’s oldest harbour office reborn as an intimate, eccentric hideaway in HafenCity. Why DNA Hotels Loves It ● One of HafenCity’s oldest surviving buildings, the former 19th-century Harbour Authority gives the hotel genuine maritime history rather than manufactured nautical nostalgia. ● With just 49 rooms, it is unusually…

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25hours Hotel HafenCity
25hours Hotel HafenCity | Hamburg

25hours Hotel HafenCity

25hours Hotel HafenCity – Hamburg, Germany Real sailors’ stories, shipyard materials and harbour-city energy shape one of 25hours’ most immersive hotels. Why DNA Hotels Loves It ● The maritime concept goes far beyond decoration: 25 real seafarers were interviewed and their stories became the narrative running through the hotel. ● Stephen Williams Associates, Eventlabs, Markus…

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25hours Hotel One Central
25hours Hotel One Central | Dubai

25hours Hotel One Central

25hours Hotel One Central, Dubai Desert Spirit Meets Urban Playfulness Why DNA Hotels Loves It ● One of Dubai's most imaginative lifestyle hotels, blending Bedouin heritage, global influences, and the unmistakably playful 25hours spirit into one unforgettable experience. ● Interiors filled with storytelling, vintage curiosities, handcrafted details, and bold design that offer a refreshing alternative…

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Hotel Saint Augustine
Hotel Saint Augustine | Houston

Hotel Saint Augustine

Hotel Saint Augustine, HoustonA village-like design retreat where architecture, landscape, and Houston’s creative spirit converge beside the Menil Collection. Why DNA Hotels Loves It ● Lake|Flato’s beautifully restrained architecture creates a rare sense of calm in one of Houston’s most culturally vibrant neighborhoods.● Post Company’s richly layered interiors balance residential warmth, surrealist touches, and exceptional…

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AC Hotel Dowtown Los Angeles
AC Hotel Downtown Los Angeles

AC Hotel Dowtown Los Angeles

AC Hotel Downtown Los Angeles Spanish Modernism Above the Energy of Downtown LA Why DNA Hotels Loves It ● Refined interiors by Yabu Pushelberg that reinterpret the AC brand’s Spanish heritage through the lens of contemporary Los Angeles. ● Calm, minimalist guestrooms that offer a sophisticated counterpoint to the theatrical energy of the adjoining Moxy…

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Santa Monica Proper Hotel
Santa Monica Proper Hotel

Santa Monica Proper Hotel

Santa Monica Proper Hotel | Los Angeles, California | USA Where Spanish Revival Heritage Meets Kelly Wearstler’s Coastal Modernism Why DNA Hotels Loves It ● A seamless blend of a 1928 Spanish Colonial Revival landmark and a contemporary glass-and-steel addition by Howard Laks Architects. ● Kelly Wearstler’s richly layered interiors reinterpret California coastal luxury through…

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St Pancras London
St. Pancras London, Autograph Collection

St Pancras London

St Pancras London, Autograph Collection | United Kingdom Victorian Grandeur Reimagined for Today Why DNA Hotels Loves It ● One of London's greatest architectural landmarks, beautifully restored from George Gilbert Scott's iconic Midland Grand Hotel. ● A thoughtful redesign that balances Gothic Revival splendour with contemporary comfort and understated luxury. ● Directly connected to St.…

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Byblos Art Hotel Villa Amistà
Byblos Art Hotel Villa Amistà | Verona

Byblos Art Hotel Villa Amistà

Byblos Art Hotel Villa Amistà – Verona, Italy A Renaissance villa in Valpolicella where Alessandro Mendini, contemporary art and Italian Baroque collide in glorious technicolour. Why DNA Hotels Loves It ● A historic Venetian villa transformed by Alessandro Mendini, creating one of Italy’s most exuberant encounters between heritage architecture and contemporary design. ● More than…

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Populus Seattle
Populus | Seattle

Populus Seattle

Populus Seattle, Washington, USA A 1907 Pioneer Square landmark reborn as a carbon-positive hotel rooted in the landscapes of the Pacific Northwest Why DNA Hotels Loves It ● The historic Westland Building has been sensitively transformed by The Miller Hull Partnership, preserving Douglas fir beams, exposed brick and century-old structure rather than replacing it with…

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W Florence
W Florence

W Florence

W Florence, Florence Where Fashion, Modernism, and Florentine Heritage Meet Why DNA Hotels Loves It ● A bold reinvention of Florence's former Grand Hotel Majestic, where 1960s Rationalist architecture meets AvroKO's fashion-inspired interiors. ● One of the city's most vibrant social destinations, combining contemporary Tuscan dining, rooftop cocktails, and W's signature energy. ● Proof that…

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