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Tired of endless surfing, scrolling and filtering finding the right place to stay? Here at DNA Hotels find our curated collection of the authentic and inspirational, our own finds plus your favourite bookmarked selection from travel and design publications. Search for experiences rather than just location, price and a place to lay your head. A hotel as a home away from home? We don't think so.
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design-led hotel

Where Design Defines the Experience

This is the heart of DNA Hotels. A design-led hotel doesn’t have to be created by a famous architect or interior designer—it can be carefully designed from the ground up or have evolved organically over decades. What matters is that everything feels connected: architecture, interiors, furniture, materials, light and atmosphere. These are hotels with a clear point of view, where design isn’t decoration or a marketing label, but part of the character of the place and the way you experience it.

Lokal Hotel Fishtown
Lokal Hotel Fishtown | Philadelphia

Lokal Hotel Fishtown

Lokal Hotel Fishtown, Philadelphia, USA Six design-led apartments built by local makers in the heart of Philadelphia’s creative Fishtown Why DNA Hotels Loves It ● Lokal’s “invisible service” concept removes the reception desk and much of traditional hotel service, replacing it with the freedom of having your own beautifully designed apartment. ● Fishtown-based True Hand…

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AC Hotel Dowtown Los Angeles
AC Hotel Downtown Los Angeles

AC Hotel Dowtown Los Angeles

AC Hotel Downtown Los Angeles Spanish Modernism Above the Energy of Downtown LA Why DNA Hotels Loves It ● Refined interiors by Yabu Pushelberg that reinterpret the AC brand’s Spanish heritage through the lens of contemporary Los Angeles. ● Calm, minimalist guestrooms that offer a sophisticated counterpoint to the theatrical energy of the adjoining Moxy…

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Santa Monica Proper Hotel
Santa Monica Proper Hotel

Santa Monica Proper Hotel

Santa Monica Proper Hotel | Los Angeles, California | USA Where Spanish Revival Heritage Meets Kelly Wearstler’s Coastal Modernism Why DNA Hotels Loves It ● A seamless blend of a 1928 Spanish Colonial Revival landmark and a contemporary glass-and-steel addition by Howard Laks Architects. ● Kelly Wearstler’s richly layered interiors reinterpret California coastal luxury through…

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St Pancras London
St. Pancras London, Autograph Collection

St Pancras London

St Pancras London, Autograph Collection | United Kingdom Victorian Grandeur Reimagined for Today Why DNA Hotels Loves It ● One of London's greatest architectural landmarks, beautifully restored from George Gilbert Scott's iconic Midland Grand Hotel. ● A thoughtful redesign that balances Gothic Revival splendour with contemporary comfort and understated luxury. ● Directly connected to St.…

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VELA be Bangkok Siam
VELA be Bangkok Siam

VELA be Bangkok Siam

VELA be Bangkok Siam - Thailand Where Minimalist Design Meets Bangkok’s Creative Energy Why DNA Hotels Loves It ● A playful interpretation of urban minimalism in one of Bangkok’s most dynamic neighbourhoods. ● Smart, efficient design that delivers style and personality without unnecessary excess. ● Perfectly positioned in the heart of Siam, placing Bangkok’s creative,…

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Morgan & Mees Rotterdam
Morgan & Mees | Rotterdam

Morgan & Mees Rotterdam

Morgan & Mees Rotterdam | The Netherlands Bauhaus Heritage with a Contemporary Soul Why DNA Hotels Loves It ● A beautifully restored 1938 Bauhaus landmark that balances architectural heritage with boutique warmth. ● Just 20 individually designed rooms, creating an intimate atmosphere that feels more like a stylish residence than a hotel. ● A lively…

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Byblos Art Hotel Villa Amistà
Byblos Art Hotel Villa Amistà | Verona

Byblos Art Hotel Villa Amistà

Byblos Art Hotel Villa Amistà – Verona, Italy A Renaissance villa in Valpolicella where Alessandro Mendini, contemporary art and Italian Baroque collide in glorious technicolour. Why DNA Hotels Loves It ● A historic Venetian villa transformed by Alessandro Mendini, creating one of Italy’s most exuberant encounters between heritage architecture and contemporary design. ● More than…

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Nomos Hotel
Nomos Hotel | Rome

Nomos Hotel

Nomos Hotel | Rome, Italy An intimate sanctuary where a former monastery has been transformed into one of Rome's purest expressions of architectural minimalism. Why DNA Hotels Loves It ● A remarkable conversion of an 18th-century Franciscan monastery into a serene design hotel centred on craftsmanship and material honesty. ● Interiors by designer Henry Timi…

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Blackbird New Orleans
Blackbird New Orleans

Blackbird New Orleans

The Blackbird Hotel, New Orleans, Louisiana Southern Gothic shadows, intimate rooms and a courtyard pool in the Lower Garden District. Why DNA Hotels Loves It ● Just 13 individually designed rooms turn a historic New Orleans property into an intimate alternative to the city’s larger hotels. ● Jeannine Jacob Interiors mixes Southern Gothic drama with…

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Ace Hotel Seattle
Ace Hotel Seattle

Ace Hotel Seattle

Ace Hotel Seattle, Washington, USA The original Ace: a former maritime workers’ lodging that helped rewrite the rules of boutique hospitality Why DNA Hotels Loves It ● Opened in 1999 by Alex Calderwood, Wade Weigel and Doug Herrick, this 28-room Belltown original became the blueprint for the entire Ace Hotels philosophy. ● Whitewashed brick, soaring…

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Populus Seattle
Populus | Seattle

Populus Seattle

Populus Seattle, Washington, USA A 1907 Pioneer Square landmark reborn as a carbon-positive hotel rooted in the landscapes of the Pacific Northwest Why DNA Hotels Loves It ● The historic Westland Building has been sensitively transformed by The Miller Hull Partnership, preserving Douglas fir beams, exposed brick and century-old structure rather than replacing it with…

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G-Rough
G-Rough | Rome

G-Rough

G-Rough, Rome Rome's Decadent Design Den Why DNA Hotels Loves It ● A remarkable 17th-century palazzo transformed into one of Rome's boldest design hotels, where original patina and mid-century Italian masterpieces coexist in perfect tension. ● An extraordinary collection of vintage furniture by Gio Ponti, Ico Parisi, Guglielmo Ulrich, Silvio Cavatorta, and other Italian design…

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