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Tired of endless surfing, scrolling and filtering finding the right place to stay? Here at DNA Hotels find our curated collection of the authentic and inspirational, our own finds plus your favourite bookmarked selection from travel and design publications. Search for experiences rather than just location, price and a place to lay your head. A hotel as a home away from home? We don't think so.
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design-led hotel

Where Design Defines the Experience

This is the heart of DNA Hotels. A design-led hotel doesn’t have to be created by a famous architect or interior designer—it can be carefully designed from the ground up or have evolved organically over decades. What matters is that everything feels connected: architecture, interiors, furniture, materials, light and atmosphere. These are hotels with a clear point of view, where design isn’t decoration or a marketing label, but part of the character of the place and the way you experience it.

W Florence
W Florence

W Florence

W Florence, Florence Where Fashion, Modernism, and Florentine Heritage Meet Why DNA Hotels Loves It ● A bold reinvention of Florence's former Grand Hotel Majestic, where 1960s Rationalist architecture meets AvroKO's fashion-inspired interiors. ● One of the city's most vibrant social destinations, combining contemporary Tuscan dining, rooftop cocktails, and W's signature energy. ● Proof that…

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1336 894 Chiel
MOB HOTEL Lyon Confluence
MOB HOTEL Lyon Confluence

MOB HOTEL Lyon Confluence

MOB HOTEL Lyon Confluence | France A Community-Driven Hotel Where Creativity Shapes Everyday Hospitality Why DNA Hotels Loves It ● Cyril Aouizerate extends the MOB philosophy beyond Paris, creating a hotel where culture, sustainability, and community are as important as the guestrooms. ● Raw concrete, natural wood, bold graphics, and relaxed communal spaces give the…

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1024 683 Chiel
The Shelborne
The Shelborne by Proper | Miami Beach

The Shelborne

The Shelborne by Proper - Miami Beach, USA A Mid-Century Landmark Reimagined Through Art, Architecture, and Tropical Modernism Why DNA Hotels Loves It ● A $100 million restoration revives one of Miami Beach’s defining Art Deco and Miami Modern landmarks while preserving its architectural identity. ● ADC Atelier combines honed travertine, Perlino marble, warm timber,…

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375 500 Chiel
The Nickel Hotel
The Nickel Hotel | Charleston, South Carolina

The Nickel Hotel

The Nickel Hotel, Charleston, South Carolina, USA Charleston tradition reworked with European elegance and contemporary Southern soul. Why DNA Hotels Loves It ● A rare new-build that already feels embedded in Charleston, with Morris Adjmi Architects translating the city’s wrought iron, courtyards and historic townhouses into something contemporary rather than faux-historic. ● The spectacular central…

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1024 741 Chiel
Le Méridien Ra Beach Hotel & Spa
Le Méridien Ra Beach Hotel & Spa | El Vendrell, Spain

Le Méridien Ra Beach Hotel & Spa

Le Méridien Ra Beach Hotel & Spa – El Vendrell, Spain A monumental 1929 seaside landmark where Catalan heritage, contemporary design and Mediterranean wellness meet. Why DNA Hotels Loves It ● A remarkable 300-metre beachfront landmark, originally built in 1929 as a children’s sanatorium and sensitively transformed into a resort that still celebrates its architectural…

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1024 683 Chiel
Les Roches Rouges
Les Roches Rouges | Saint-Raphaël, French Riviera

Les Roches Rouges

Les Roches Rouges | Saint-Raphaël, France Mid-century Riviera modernism where white architecture, red Estérel rock and the Mediterranean meet Why DNA Hotels Loves It ● Festen Architecture stripped away decades of additions to rediscover the clean modernist character of the original 1950s seaside hotel. ● Vintage pieces by Pierre Chareau, Willy Guhl and Charlotte Perriand…

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1024 683 Chiel
Stamna Sifnos
Stamna Sifnos

Stamna Sifnos

Stamna Sifnos | Greece Where Cycladic Craft Meets Contemporary Calm Why DNA Hotels Loves It ● A design-led retreat that celebrates Sifnos’ rich pottery heritage through architecture, materials, and craftsmanship. ● Intimate in scale, with just 20 rooms surrounded by gardens, terraces, and sweeping Aegean views. ● A thoughtful balance of modern luxury, sustainability, and…

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750 1000 Chiel
Jupiter Hotel Portland
Jupiter Hotel | Portland, Oregon

Jupiter Hotel Portland

Jupiter Hotel, Portland, Oregon, USA Portland’s original indie motel reborn with murals, music and East Burnside attitude Why DNA Hotels Loves It ● A 1960s motor lodge that helped pioneer Portland’s affordable, design-conscious boutique hotel scene when it reopened as Jupiter in 2004. ● The 81 renovated rooms celebrate music through 11 floor-to-ceiling murals, alongside…

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1024 683 Chiel
SLS Barcelona
SLS Barcelona

SLS Barcelona

SLS Barcelona | Spain A Playful Waterfront Resort Where Contemporary Design Takes Centre Stage Why DNA Hotels Loves It ● A striking collaboration between b720 Fermín Vázquez Arquitectos, Rockwell Group, AvroKO, and AIME Studios. ● Bold interiors that embrace theatrical design while maintaining genuine comfort and sophistication. ● A vibrant waterfront destination combining rooftop pools,…

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1400 933 Chiel
PURO Wrocław Stare Miasto
PURO Wrocław Stare Miasto

PURO Wrocław Stare Miasto

PURO Wrocław Stare Miasto, Poland A contemporary city hotel where Scandinavian restraint, Polish art, and Wrocław’s layered urban character come together Why DNA Hotels Loves It ● The clean-lined new-build architecture sits confidently within Wrocław’s historic Four Denominations District without attempting to imitate its Gothic and 19th-century neighbours. ● Warm timber, soft fabrics, contemporary furniture,…

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1019 768 Chiel
PURO Poznań Stare Miasto
PURO Poznań Stare Miasto

PURO Poznań Stare Miasto

PURO Poznań Stare Miasto, Poland A contemporary Old Town hotel refreshed by Holloway Li with limestone, art-nouveau references, and a distinctly local design language Why DNA Hotels Loves It ● London studio Holloway Li’s 2024 redesign gives the hotel a stronger sense of place, drawing on Poznań’s art-nouveau townhouses, industrial history, and public spaces. ●…

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1024 683 Chiel
PURO Warszawa Stare Miasto
PURO Warszawa Stare Miasto

PURO Warszawa Stare Miasto

PURO Warsaw Stare Miasto, Poland A Scandinavian-modern retreat where GamFratesi brings calm, craft, and contemporary Polish culture to the edge of Warsaw’s Old Town Why DNA Hotels Loves It ● Copenhagen-based GamFratesi gives the hotel a distinctly residential character, combining custom furniture with pieces by GUBI, Louis Poulsen, &Tradition, Carl Hansen & Søn, Fredericia, Eikund,…

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576 768 Chiel