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Tired of endless surfing, scrolling and filtering finding the right place to stay? Here at DNA Hotels find our curated collection of the authentic and inspirational, our own finds plus your favourite bookmarked selection from travel and design publications. Search for experiences rather than just location, price and a place to lay your head. A hotel as a home away from home? We don't think so.
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design-led hotel

Where Design Defines the Experience

This is the heart of DNA Hotels. A design-led hotel doesn’t have to be created by a famous architect or interior designer—it can be carefully designed from the ground up or have evolved organically over decades. What matters is that everything feels connected: architecture, interiors, furniture, materials, light and atmosphere. These are hotels with a clear point of view, where design isn’t decoration or a marketing label, but part of the character of the place and the way you experience it.

25hours Hotel The Olympia
25hours Hotel Sydney The Olympia

25hours Hotel The Olympia

25hours Hotel The Olympia | Sydney, Australia A Heritage Cinema Reborn as a Flamboyant Celebration of Sydney’s Creative Spirit Why DNA Hotels Loves It ● A heritage-listed former cinema transformed into a theatrical design hotel that embraces Oxford Street’s history of performance, nightlife, and queer culture. ● 109 guestrooms divided between the colourful Dreamers and…

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1 Hotel Melbourne
1 Hotel Melbourne

1 Hotel Melbourne

1 Hotel Melbourne | Australia Where Industrial Heritage Meets Biophilic Luxury Why DNA Hotels Loves It ● A remarkable transformation of Melbourne’s last surviving heritage goods shed into a sustainable luxury hotel. ● Thousands of reclaimed materials and living plants create one of the most ambitious examples of biophilic hospitality in Australia. ● Proof that…

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Amyth of Nicosia
Amyth of Nicosia

Amyth of Nicosia

Amyth of Nicosia – Cyprus A restored historic villa inside Nicosia’s Venetian walls, where painted ceilings, Cypriot craftsmanship and contemporary restraint tell the story of the capital. Why DNA Hotels Loves It ● A remarkable ten-room villa in Nicosia’s Old Town, restored with its painted ceilings, traditional tiles, carved woodwork, shutters and original architectural character…

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Hotel Sevilla
Hotel Sevilla | Mérida, Mexico

Hotel Sevilla

Hotel Sevilla | Mérida, MexicoA 16th-century colonial villa where ruin, ritual, and contemporary Mexican design converge in the historic heart of Mérida. Why DNA Hotels Loves It ● Zeller & Moye’s sensitive transformation preserves the building’s layered history while introducing bold contemporary interventions. ● A rare Mexican design hotel where colonial architecture, tropical courtyards, raw…

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The Newman
The Newman | London

The Newman

The Newman | London, United Kingdom Art Deco Elegance in the Heart of Fitzrovia Why DNA Hotels Loves It ● A design-led boutique hotel that captures the artistic heritage and independent spirit of Fitzrovia. ● Beautiful interiors by Lind+Almond, inspired by the neighbourhood's Art Deco architecture and creative history. ● Sophisticated restaurants, a characterful cocktail…

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BAR10ZIMMER
BAR10ZIMMER | Dornbirn, Austria

BAR10ZIMMER

BAR10ZIMMER | Dornbirn, AustriaA beautifully restored townhouse where historic character, thoughtful design, and understated hospitality come together in the heart of Vorarlberg. Why DNA Hotels Loves It ● A sensitive transformation of a historic bakery and townhouse into one of Austria’s most quietly compelling boutique hotels. ● Minimalist interiors that prove luxury can be achieved…

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Debaines Hotel Santiago
Desbaines Hotel Santiago | Chile

Debaines Hotel Santiago

Debaines Hotel Santiago – Santiago, Chile Where Heritage, Architecture, and Contemporary Chilean Design Converge Why DNA Hotels Loves It ● A thoughtful architectural dialogue between Santiago’s historic Teatro Municipal and a striking contemporary glass structure. ● Sophisticated interiors that celebrate Chilean craftsmanship, natural light, and material authenticity. ● One of the most culturally connected addresses…

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Hasenberg Lodge
Hasenberg Lodge | Walenstadt, Switzerland

Hasenberg Lodge

Hasenberg Lodge | Walenstadt, Switzerland A private 1970s modernist hideaway suspended between the Walensee and the Churfirsten Why DNA Hotels Loves It ● A remarkably intact 1971 modernist interpretation of the Swiss chalet, restored by architect-owners Michelle Corrodi and Roger Zogg without designing away its original character. ● The interiors are a highly personal composition…

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The Lince Santa Clara
The Lince Santa Clara | Vila do Conde

The Lince Santa Clara

The Lince Santa Clara, Vila do Conde Where a centuries-old convent overlooking the Ave River has been transformed into one of northern Portugal’s most elegant contemporary retreats. Why DNA Hotels Loves It ● A beautifully restored 14th-century convent where historic architecture meets refined contemporary design. ● Peaceful riverside setting within walking distance of Vila do…

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Octant Hotels Douro
Octant Hotels Douro | Castelo de Paiva

Octant Hotels Douro

Octant Hotels Douro, Castelo de Paiva, Portugal A striking modern retreat where architecture, landscape, and the Douro River become one seamless experience Why DNA Hotels Loves It ● A spectacular piece of contemporary architecture by João Serôdio, sculpted into the hillside to maximise uninterrupted views of the Douro River. ● Warm minimalist interiors by Cristina…

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Casa del Limonero
Casa del Limonero | Seville

Casa del Limonero

Casa del Limonero, Seville, Spain Where Andalusian Heritage Meets Contemporary Art Why DNA Hotels Loves It ● A magnificent 15th-century Sevillian palace where centuries of architecture coexist with one of the city's most remarkable private contemporary art collections. ● Fourteen individually designed suites filled with museum-quality furniture, antiques, and works by internationally acclaimed artists. ●…

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Mayfair House Hotel & Garden
Mayfair House Hotel & Garden | Coconut Grove, Miami

Mayfair House Hotel & Garden

Mayfair House Hotel & Garden | Coconut Grove, Miami | Florida, USAWhere tropical modernism, artistic eccentricity, and Coconut Grove’s bohemian soul bloom beneath a canopy of palms. Why DNA Hotels Loves It ● One of America’s great architectural hotels, originally designed by Kenneth Treister and beautifully revived without sacrificing its extraordinary character. ● A rare…

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